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Mike Keenan

Associate professor
Division of Human Nutrition and Food
School of Human Ecology
209 Knapp Hall
Louisiana State University and LSU AgCenter
Baton Rouge, LA 70803
Phone: 225-578-1708
Fax: 225-578-4443
Email: mkeenan@agctr.lsu.edu


Personal Philosophy
I thank Jesus for making a guy like me look smart.


Research Interests:
The health effects of dietary fermentable fibers, specifically resistant starches. My interests include prevention and treatment of chronic diseases with a focus of research at the molecular level.


Current Projects:
Gut Microflora and our Health


Recent and Notable Publications:

Journal Articles:
Shen. L,Keenan MJ, Martin RJ, Tulley RT, Raggio AM, McCutcheon KL, Zhou J. (2008) Dietary resistant starch increases hypothalamic POMC expression independent of capsaicin-sensitive neurons in rats. Obesity (in press).


Zhou J, Martin RJ, Tulley RT, Raggio AM, McCutcheon KL, Shen L, Danna SC, Tripathy S, Hegsted M, Keenan MJ. Dietary resistant starch up-regulates total GLP-1 and PYY in a sustained daylong manner through fermentation in rodents. American Journal of Physiology Endocrinology and Metabolism (September 16, 2008). Doi:10.1152/ajpendo.90637.2008.


Keenan MJ, Martin RJ, Tulley RT, McCutcheon KL, Raggio AM, Williams C, Bateman HG, Tripathy S, Chen JY, Mumphrey S, Zhou J (2009) Benefits of fermentable carbohydrates in rodent models. In: Recent Advances in Probiotics and Prebiotics in Foods: Product Applications and Wellbeing. (In press).


Abstracts:
Senevirathne RN, Janes ME, Zhou J, Scott Sr. RR, McCutcheon KL, Martin RJ, Raggio AM, Tulley RT, Keenan MJ (2008) Dietary resistant starch promotes a greater potential benefical:pathogenic bacteria ratio. Obesity 16 Suppl:S266.


Zhou J, Martin RJ, Raggio AM, Shen L, Lissy E, McCutcheon KL, Tulley RT, Keenan MJ. (2008) Dietary resistant starch increased energy expenditure and improved glucose tolerance in C57BL/6J mice. Obesity 16 Suppl:S266.


Senevirathne RN, Janes ME, Martin RJ, Zhou J, Raggio AM, Tulley RT, Keenan MJ (2008) Populations of Lactobacillus spp and Clostridium perfingens in rats fed resistant starch. American Society for Microbiology Annual Meeting Abstract on CD-ROM, ISBN 978-1555814939.


Teaching:
HUEC 4021 Contemporary Topics in Nutrition (1 hour)
HUEC 7002 Micronutrients (2 hours)
HUEC 7010 Food and Nutrition Seminar (1 hour)
HUEC 7011 Current Advances in Food and Nutrition (1-3 hours)
Topics vary: Metabolic integration, Nutrigenomics, etc.
HUEC 7017 Advanced Human Nutrition (3 hours)


Recent Professional and Notable Activities:

Presentations and Attendance at Conferences:
Keystone Conference: Joint Conferences – Diabetes: Molecular Genetics, Signaling Pathways and Integrated Physiology; and – Obesity: Peripheral and Central Pathways Regulating Energy Homeostasis.  Keystone, Colorado, January 2007

North American Association for the study of Obesity (NAASO) Annual Conference, Boston, Massachusetts, October 2006

Experimental Biology Annual Conference, San Francisco, California, April 2006


Honors and Awards:

2007 Invited speaker on Health Implications for Resistant Starch at the American Chemical Society Meeting
2007 Invited Speaker at a symposium on The New Fiber Story: Natural Resistant Starch at American Dietetics Association Meeting
2007

Awarded the School of Human Ecology Outstanding Research Award

2007

A member of the “Louisiana Serving Food Safely” team that won the Denver T. and Ferne Loupe Extension Team Award form the LSU AgCenter

2008

Invited Speaker at a symposium on Obesity in the Developed and Developing World for the American Oil Chemists Meeting


Grants:
Keenan, Michael, Hegsted, Maren, Bateman, H. Gale, Martin, Roy, Tulley, Richard, Zhou, Jun; National Starch and Chemical Company, $117,000; and Biotechnology AgCenter Interdisciplinary Team (BAIT); $15,000; 2005-2007; Gene arrays to determine novel satiety signals in the rat: response to feeding high amylose resistant starch


Martin, Roy, Zhou, Jun, Keenan, Michael; NIH R21 DK 073403; $404,250; 2006-2008; Dietary Resistant Starch: The Role of PYY and GLP-1 in Energy Balance

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