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Mike Keenan
Associate professor
Division of Human Nutrition and Food
School of Human Ecology
209 Knapp Hall
Louisiana State University and LSU AgCenter
Baton Rouge, LA 70803
Phone: 225-578-1708
Fax: 225-578-4443
Email: mkeenan@agctr.lsu.edu
Personal Philosophy
I thank Jesus for making a guy like me look smart.
Research Interests:
The health effects of dietary fermentable fibers, specifically resistant starches. My interests include prevention and treatment of chronic diseases with a focus of research at the molecular level.
Recent and Notable Publications:
Journal Articles:
Keenan MJ, Zhou J, McCutcheon KL, Raggio AM, Bateman HG, Todd E, Jones CK, Tulley RT, Melton S, Martin RJ, Hegsted M. (2006) Effects of resistant starch, a non-digestible fermentable fiber, on reducing body fat. Obesity 14:1523-1534.
Zhou J, Hegsted M, McCutcheon KL, Keenan MJ, Xi X, Raggio AM, Martin RJ (2006) Peptide YY and proglucagon mRNA expression patterns and regulation in the gut. Obesity 14:683-689.
Abstracts:
Keenan MJ, Zhou J, Raggio AM, McCutcheon KL, Newman SS, Tulley RT, Martin RJ, Brown I, Birkett A, Hegsted M (2007) Altering gut hormones and cell proliferation pathway factors expressions by resistant starch leads to reduced body weight and body fat in rats. Keystone Conference Abstract Book, page 79, January 2007
Keenan MJ, Zhou J, Raggio AM, McCutcheon KL, Newman SS, Tulley RT, Martin RJ, Brown I, Birkett A, Hegsted M (2006) Preliminary microarray analysis of genes from cecal cells of resistant starch fed rats. Obesity 14 Suppl:A206.
Zhou J, Keenan MJ, Hegsted M, Danna S, Tulley RT, Martin RJ (2006) Mechanistic study: how resistant starch modulates PYY and proglucagon expression. Obesity 14 Suppl: A133.
Keenan MJ, Raggio AM, Zhou J, McCutcheon KL, Tulley RT, Bateman HG, Martin RJ, Hegsted M Resistant starch reduces abdominal fat more than energy dilution with nonfermentable fiber. (2006) Experimental Biology meeting abstracts [on CD –ROM]. The FASEB Journal, 20 Abstract #137.1.
Keenan MJ, Mumphrey SM, Lomax LL, Raggio AM, McCutcheon KL, Zhou J, Bateman HG, Tulley RT, Martin RJ, Hegsted M Resistant starch and fructooligosaccharide improve gut histology and alter gut signaling in rats. (2006) Experimental Biology meeting abstracts [on CD –ROM]. The FASEB Journal, 20 Abstract #137.2.
Teaching:
HUEC 4021 Contemporary Topics in Nutrition (1 hour)
HUEC 7002 Micronutrients (2 hours)
HUEC 7010 Food and Nutrition Seminar (1 hour)
HUEC 7011 Current Advances in Food and Nutrition (1-3 hours)
Topics vary: Metabolic integration, Nutrigenomics, etc.
HUEC 7017 Advanced Human Nutrition (3 hours)
Recent Professional and Notable Activities:
Presentations and Attendance at Conferences:
Keystone Conference: Joint Conferences – Diabetes: Molecular Genetics, Signaling Pathways and Integrated Physiology; and – Obesity: Peripheral and Central Pathways Regulating Energy Homeostasis. Keystone, Colorado, January 2007
North American Association for the study of Obesity (NAASO) Annual Conference, Boston, Massachusetts, October 2006
Experimental Biology Annual Conference, San Francisco, California, April 2006
Honors and Awards:
| 2006 |
Best Research Team Award from the Nutrition and Brain Division of the Pennington Biomedical Research Center |
| 2006 |
Best Research Paper Award from the Nutrition and Brain Division of the Pennington Biomedical Research Center |
| 2006 |
Invited speaker for the Nutrition and Brain Division of the Pennington Biomedical Research Center to present our research team's current research for our above stated awards |
Grants:
Keenan, Michael, Hegsted, Maren, Bateman, H. Gale, Martin, Roy, Tulley, Richard, Zhou, Jun; National Starch and Chemical Company, $117,000; and Biotechnology AgCenter Interdisciplinary Team (BAIT); $15,000; 2005-2007; Gene arrays to determine novel satiety signals in the rat: response to feeding high amylose resistant starch
Martin, Roy, Zhou, Jun, Keenan, Michael; NIH R21 DK 073403; $404,250; 2006-2008; Dietary Resistant Starch: The Role of PYY and GLP-1 in Energy Balance
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